Storage pool disease is a rare congenital platelet-function disorder characterized by the absence of platelet dense granules and their contents, which causes prolongation of bleeding time. This report describes extraction of the bilateral third molars of the mandible and maxilla in a 22-year-old woman with storage pool disease. A conventional surgical technique was used. No evidence of collagen, ADP, or epinephrine-induced platelet aggregation was observed. Electron microscopy revealed the absence of dense granules. One hour after teeth extraction, the prolonged postoperative bleeding was controlled with the use of hemostatic preparations of gelatin and cellulose; a small gauze pack was placed over the socket and an anti-plasmin agent was injected.