Previous studies have shown that the ratio of non-Hodgkin's disease (NHL) to Hodgkin's disease is high in Japan (almost 90%). T-cell lymphoma has a lower incidence and a worse prognosis than Bcell lymphoma.
A 63-year old man was referred to our department because of pain in the left side of the maxilla. Clinical examination revealed swelling and an ulcer on the left molar gingiva. A computed tomograhic scan showed a lesion extending from the left side of the maxillary gingiva to the left paranasal sinuses. Histopathologically, diffuse large-cell malignant lymphoma was diagnosed. Immunophenotypic analysis of surface markers disclosed T-cell features. Laboratory examination indicated high LDH values and a reversed ratio of neutrophils and lymphocytes.
The patient received combination chemotherapy with CHOP and radiotherapy.
The tumor disappeared after therapy, and the patient has been under observation for 4 years without recurrence.
