日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
自己血からの多血小板血漿 (PRP: Platelet Rich Plasma) を用いた上顎前歯部自家骨移植の1例
インプラント治療における骨移植への有用性
澤 裕一郎川野 大福井 克仁中山 敦史土井田 誠宮城島 俊雄
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2000 年 46 巻 6 号 p. 372-374

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Bone grafts are useful for the placement of implants in atrophic bone in edentulous regions. Usually, grafted bone undergoes resorption and provides inadequate support for implants. The guided bone regeneration (GBR) method can prevent resorption of grafted bone; however, GBR has some disadvantages, including exposure of the membrane and infection. Platelet rich plasma (PRP) accelerates wound healing by autologous growth factors. We consider growth factors of PRP to promote sufficient bone for implants. In this study, we used PRP gel to graft, bone harvested from the chin to the anterior maxillary region, which had undergone resorption. After 14 weeks, we decided that there was sufficient bone in the region on computed tomographic examination. After 16 weeks, implants were able to be placed, despite bone resorption. Biopsy of bone specimens revealed active osteogenesis and bone remodeling. Our results suggest that PRP could accelerate bone healing and remodeling, but could not prevent bone resorption in a similar manner to GBR. We confirmed that PRP gel is beneficial at the time of bone grafting for implants.

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