Cowden's disease is an autosomal dominant syndrome associated with diverse benign and malignant tumors. A rare case of Cowden's disease is reported. The patient was 64-year-old woman who was given a diagnosis of Cowden's disease by her physician. She complained of discomfort in the gingival mucosa and had a number of papules on the face, limbs, and gingiva. Pathological examination of the oral papules showed fibrous hyperplasia. We vaporized the papules on the gingiva with a KTP-laser. Gingival papillomatosis did not recur during follow-up. The patient was satisfied with the outcome of treatment.
