Central giant cell granuloma (CGCG) originating in the ramus of the mandible is relatively rare. We report an atypical case of an 8-year-old boy with CGCG of the left ramus of the mandible. The lesion was first noticed as a slightly painful swelling 1 week before presentation. Orthopantomography showed a poorly defined, unilocular radiolucent lesion. Computed tomography and magnetic resonance imaging, especially T2-weighted images, described the lesion definitely. Enucleation of the lesion was performed under general anesthesia on January 12, 1999. Because a curettage specimen histologically showed multiple granulomatous nodules consisting of proliferations of fibroblasts and infiltrates of macrophages and inflammatory cells as well as numerous multinuclear giant cells, we diagnosed CGCG. The postoperative course was uneventful after conservative management.
