2004 年 50 巻 10 号 p. 620-623
The Laugier-Hunziker-Baran syndrome represents a rare acquired pigmentary disorder of the lips, oral mucosa, and nails. We report two cases showing acquired, benign, macular hyperpigmentation of the buccal mucosa, lips, and fingers. The patients had no family history related to this condition and no history of gastrointestinal disorders or generalized skin disorders. Because of its clinical importance, Laugier-Hunziker-Baran syndrome should be included in the differential diagnosis of pigmentary disorders of the oral mucosa with associated nail involvement. It is particularly important to differentiate this condition from Peutz-Jeghers syndrome.