The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
Short Communications
Pharmacological Evaluation of a New Laser Blood Flowmeter for Measuring Coronary Blood Flow, Assessed in the Canine Isolated, Blood-Perfused Ventricular Tissue Preparation in Comparison With an Electromagnetic Flowmeter
Atsushi SugiyamaShunji TakehanaKeitaro Hashimoto
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ジャーナル フリー

1999 年 80 巻 3 号 p. 263-266

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抄録
A new portable-type laser blood flowmeter was recently developed for measuring the blood flow in vessels. The sensitivity and specificity of the laser flowmeter was assessed in comparison with the well-established electromagnetic flowmeter using a canine isolated, blood-perfused ventricular tissue preparation. The laser flowmeter can record the phasic pattern of the coronary blood flow like the electromagnetic flowmeter. The extent of the changes after intracoronary administration of ACh and angiotensin II as well as coronary occlusion was almost identical between these two methods. These results suggest that the new laser flowmeter may possess potential utilities in both basic experimental and clinical practices.
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© The Japanese Pharmacological Society 1999
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