抄録
Tramadol and low-dose oxycodone is used for moderate cancer pain. There are no reports comparing oxycodone and tramadol in patients with cancer pain in the second step of the WHO pain ladder. We conducted a clinical trial of low dose oxycodone versus tramadol for the initial control of patients with moderate cancer pain. Tramadol was equivalent to oxycodone in pain improvement rate and titration completion rate. However, the incidence of side effects was lower in the tramadol group. The rate was 13.3% in the tramadol, and 81.2% in the oxycodone. In conclusion, the results of this trial suggest that tramadol has a lower risk of side effects than oxycodone.
