抄録
The purpose of this study was to compare surgical-site infection (SSI) rates in women who had prophylactic antibiotics for 3 to 4 days (Group 3-4 days) versus 1 day (Group 1 day) of Flomoxef sodium (FMOX) in obstetrical and gynecological surgery and to identify risk factors for SSI.
This retrospective study was conducted from November 2011 through November 2012 in the International University of Health and Welfare Hospital. The main outcome measure was the rate of incidence of SSI, and backgrounds were compared between patients with and without SSIs.
There were 266 patients (110 in the Group 3-4 days and 156 in the Group 1 day). A total of 6 cases had SSIs: 2 cases (1.8%) in the Group 3-4 days and 4 cases (2.6%) in the Group 1 day (P = 0.516). Those 6 cases with SSIs included more patients with a past history of infection (83% vs 23%; Odds Ratio, 16.7; 95% confidence interval, 1.91-145; P = 0.004) and with BMI > 30 kg/m2 (50% vs 9%; Odds Ratio, 10.8; 95% confidence interval, 2.06-56.8; P = 0.012).
Both administration for 3 to 4 days and 1 day of FMOX had similar efficacy in the prevention of SSI in obstetrical and gynecological surgery. The BMI level was a known risk factor, but the results also showed that a past history of infection could become a new risk factor for SSI.
