抄録
Use of a closed system drug transfer device is effective in decreasing the exposure of medical staff to anti-cancer drugs. However, the exposure of a syringe plunger to anti-cancer drugs during preparation has not been validated. Therefore, we conducted a study to examine the drug pollution of the syringe plunger after cyclophosphamide (CPA) preparation. In the present study, CPA were detected in all syringe plungers that had been used in CPA preparation (median: 2.97 ng, range: 0.681-68.2 ng). Therefore, using the same syringe for administering two or more injections could increase the risk of CPA exposure for the medical staff.
