薬剤師の病棟業務時間とプレアボイド件数の相関

抄録

PreAVOID (“Prevent and avoid an adverse drug reaction”) is a pharmaceutical intervention that contributes to the improvement of drug safety and efficacy. It is considered important for pharmacists to spend time in the ward and carry out numerous PreAVOID interventions. At present, however, there have been no reports on the relationship between working hours of pharmacists in the ward and the number of PreAVOID interventions performed. Therefore, we investigated this relationship in Chiba University Hospital.

The working hours of pharmacists in each ward gradually increased and were 13.5-38.3 h per week from April 2015 to March 2017. The number of PreAVOID interventions also increased from 630 in fiscal year 2015 to 1116 in fiscal year 2016. The number of interventions that prevented adverse drug reactions increased from 402 in fiscal year 2015 to 550 in fiscal year 2016. The number of interventions that improved drug efficacy increased from 188 in fiscal year 2015 to 508 in fiscal year 2016. The working hours of pharmacists in the ward showed a positive and statistically significant correlation with the number of PreAVOID interventions (r = 0.688, P < 0.001). Therefore, our findings indicate that longer working hours of pharmacists in the ward probably result in an improvement in the efficacy as well as safety of drug therapy in association with increased PreAVOID interventions. Thus, it is important to ensure that pharmacists spend sufficient time in the ward in order to contribute to the improvement of drug safety and efficacy through PreAVOID interventions.