抄録
Pharmaceutical properties of 6 commercial products of 0.02% fluorometholone ophthalmic suspension were studied. The following results were obtained:
1) All the products had similar pH values and osmotic pressures within the appropriate range, except one product which showed very high viscosity. 2) Foam might have been generated by shaking in dropped eye lotions. 3) The products in small particle sizes seemed to show a good suspension. 4) Four products were redispersed by not more than 5 shakings, while the remaining products required about 10 to 30 shakings.
Redispersion of all the products was affected by temperature and standing time. Large visible particles were observed occasionally in 4 products when allowed to stand at 60°.
