At Osaka University Hospital, trace element injections for intravenous hyperalimentation (IVH) were prepared and quality tests were conducted on their content uniformity and sterility. The composition of the injections was: IVH-Zn: Zn 20μmal; IVH-M: Zn 20μmol, Mn 40μmol, Cu 5μmol, I 1μmol. The ingredients were filtrated through 0.45μm membrane filter, filled and wet-sterilized at 121° for 20 minutes. The content uniformity was determined by Atomic Absorption Spectrophotometry. The standard contents of the elements in the injections were determined in the range of 90 to 110w/v%. All lots were negative to Sterility Test (J. P. IX).
