病院薬学
Online ISSN : 2185-9477
Print ISSN : 0389-9098
ISSN-L : 0389-9098
高力ロリー輸液の基本輸液剤 (IVH-1A,-1B) の製剤学的検討
混合調製時の微生物汚染と微粒子汚染について
笠原 伸元佐藤 健太郎倉田 義昭鈴木 芳郎上野 達也杉本 真理山路 昭紀氏 汎恵大西 昇平岡 栄一
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1978 年 4 巻 3 号 p. 114-119

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Basic solutions (IVH-1A and -1B) for hyperalimentation were compared with control solutions prepared in combination of various agents, in respect of: 1) time required for admixture; 2) microbial contamination, and 3) particulate contamination to be caused during the admixture. The results: 1) The time required for admixture of a bottle of IVH-1A solution averaged 8 min and 38 sec shorter than that for the 1A control solution, and the time for IVH-1B solution was 8 min and 8 sec shorter than that for the 1B control. When 5 bottles of the 2 basic solutions were prepared respectively in as efficient manner as possible, the time for admixture of IVH-1A solution was 44 min and 26 sec shorter on average than that for its control solution, and the time for IVH-1B solution was 39 min and 47 sec shorter than the control. Thus, IVH solutions were easier than the control solutions to prepare in large number of bottles. 2) In all of 200 each bottles of respective solutions prepared, microbial contamination was not detected. 3) The particle count in IVH-1A solution was about one 4th of that in the 1A control, and the count in IVH-1B solution was about one 6th of the 1B control.

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