抄録
The stability of vitamin B2 (riboflavin phosphate sodium) in infusion solution was studied in consideration of the practical condition in hospitals. When mixed in infusion solution, vitamin B2 (10mg) was photodecomposed, showing the residual rate 80% at 2000 lux for 3 hours. This decomposition was inhibited by the addition of ascorbic acid and in infusion solutions of amino acids. Flavineadenine dinucleotide was more stable than vitamin B2. As a main degradation product of vitamin B2 in infusion solution, lumichrome was identified by high-speed liquid chromatography. Vitamin B2 of multivitamin injection for intravenous hyperalimentation (IVH) was stable in IVH solutions.
