抄録
Due to an emergency warning from a pharmaceutical company, we evaluated the procedure of providing drug information to medical staffs. The warning was made regarding DEHP, which is a plasticizer of PVC eluted in etoposide injections, and intravenous transfusion sets made from PVC are used in such injections. We tried to determine whether or not any leaching of DEHP occurred during etoposide injection. Moreover, we investigated the properties of DEHP, the mechanism of DEHP leaching from PVC, and also inspected other medicines that may also have leaching of DEHP in PVC administration sets. As a result, no clinical evidence was found to support this urgent notice. However, passing through several years, related information became gradually clear. Therefore, in the information asked for quick offer, it was suggested that gradual and continuous information service becomes indispensable especially.
