Article ID: e09025
Database research using real-world data (RWD) is increasingly applied in clinical settings. However, applying RWD in database research without understanding its characteristics and limitations may lead to inaccurate results and inappropriate clinical decisions. To generate evidence aligned with clinical issues and translate it into practice, pharmacists must receive proper training that includes a structural understanding of RWD and the ability to define research questions, design appropriate studies, and interpret and apply findings. These components should not be taught in isolation but through a comprehensive and integrated educational approach. This paper discusses how pharmaceutical education should structure and promote database research in clinical settings, focusing on three key perspectives: understanding the characteristics of RWD, identifying clinical issues, and recognizing limitations.