ELECTROPHYSIOLOGICAL STUDIES ON THE WORKING MECHANISM OF MUSCLE WALLS OF THE STOMACH
1960 年 10 巻 4 号 p. 359-373
詳細
1960 年 10 巻 4 号 p. 359-373
Electrogastrogram was studied on the toad's stomach of which muscle walls consisted exclusively of circular fibers. The results obtained are as follows:
1) Every automatic contraction of the gastric muscle is always accompanied by the slow action potential both in situ and in isolated strip.
2) The greater part of the potential which usually precedes the muscle contractionterminates as a rule before the relaxation begins.
3) The rates of rhythm of the potentials are the same throughout the stomach. When peristaltic waves do exist, some of these basic potentials are associated with them.
4) For the development of tonic contraction it may be essential that the potentialwaves are conducted over the ring more rapidly than usual.
5) The gradients of potential and the liability of the pace-maker to occur in the direction from the greater to the lesser curvature are observed across the stomach. 6) Vagosympathetic stimulation will elicit a response pattern characterized by the increase in the magnitude and rate of rhythm of the potentials.
7) Splanchnic stimulation will elicit two kinds of response patterns, probably. excitatory and inhibitory ones. The former is characterized by increase in the conduction velocity, reversals of the direction of conduction, and increase in the rate of rhythm at times; the latter by decrease in the conductivity and asynchroni-zation of the potentials between respective functional units.
