The Japanese Journal of Physiology
Print ISSN : 0021-521X
NUCLEIC ACID CONTENT IN LIVER OF RATS TREATED WITH POSTERIOR PITUITARY HORMONE
広重 力伊藤 真次
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ジャーナル フリー

1960 年 10 巻 6 号 p. 659-665

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1. Chronic treatments with Pitressin produced increases in RNA-P and total nitrogen contents in livers of normal rats, while DNA-P content remained unchanged. Pitocin had no effect.
2. After hypophysectomy RNA-P and total nitrogen contents in liver reduced considerably; administration of growth hormone restored the decreased contents toward normal level, while Pitressin was ineffective.
3. Chronic treatments with Pitressin induced a significant enlargement of epiphyseal cartilage width of tibia in normal rats. Pitocin had no effect.
4. In hypophysectomized rats the width was markedly reduced; growth hormone, but not Pitressin, restored the narrowed width toward normal.
5. Administration of cortisone acetate produced a marked gain in liver weight and a slight increase in RNA-P content.
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© Physiological Society of Japan
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