抄録
It was observed that both cortisone pretreatment and endotoxin-conditioning are effective in preventing the specific PVP anaphylactoid shock in dogs. The latter effect was quite independent of glucocorticoid and was observable even. in adrenalectomized dogs maintained with DCA. Both procedures were found to induce an adaptive state in which cutaneous mast cells were stabilized and capillaries rendered tolerable to histamine, i. e. a state of reduced hypersensitivity.
