抄録
1) Exogenous posterior-pituitary hormone has an inhibitory effect on the release of ACTH provoked by epinephrine, histamine and cold.
2) Vasopressor fraction in the posterior-pituitary hormone has this effect, but oxytocic fraction has not.
3) Exogenous pitressin can not inhibit depletion of adrenal ascorbic acid following the administration of ACTH.
4) 5mu. of pitressin per 100g. body weight has no inhibitory effect on the release of ACTH.
5) A large amount of pitressin, more than 60mu. per 100g. body weight, causes a decrease in adrenal ascorbic acid. However, 0.02mg. of epinephrine per 100g. body weight of rats successively administered does not produce further depletion of adrenal ascorbic acid.
6) Even a large dose of pitressin can not cause any reduction of adrenal ascorbic acid concentration in hypophysectomized rats.
