Patients with Graves' disease have many signs and symptoms which are not only somatic but also psychological. Althouth there are many reports in this regard, the data thereof have been collected by more than one doctor and not always under the same condition.Subjective complaints and objective signs of patients whose Graves' disease had not been treated were studied and the results were compared with other known reports. Our data, especially case histories, were collected by only one doctor. In addition, patients with Graves' disease and other thyroid diseases were examined by CMI.The results were as follows : 1) Main subjectve complaints consisted of sweating, fatigability, palpitation, tremor and goiter. The percentage of detecting patients' complaints was higher in our data than in those of other reports. This might be due to different subjects and methods as mentioned above.2)There were differences in number between the complaints presented by patients and those checked by a doctor, the latter being 2 or 3 times more than the former. This is probably related to the patient's ability for self-observation and self-expression. We considered it very important to take detailed and precise history of the patient.3) CMI revealed a high rate (66%) of neurotic tendency in patients with Graves' disease. However, the more circulatory complaints patient had, the higher was the scores in neurotic tendency. When tremor, which is a somatic complaint, ezists, it is regarded as tension in CMI, thus making high scores in the psychic items. Caution should be taken in evaluation CMI scores of patients with Graves' disease.