Abstract
Recently default mode network has received the most attention in cognitive neuroscience. Although several studies have been made on abnormality in autism spectrum disorder using functional neuroimaging, they show conflict results. On the other hand very few attempts have been made at evaluation of default mode network using EEG/MEG. The purpose of this study is to examine for abnormality of default mode network in autism using MEG. Functional connectivity reflected by coherence with neural oscillation of source waveform revealed that the correlation in beta band between anterior and posterior cingulate cortex showed significant tendency to reduction in people with autism spectrum disorder. In addition, bond strength between anterior and posterior cingulate cortex showed significant positive correlation with “attention to detail” and “communication skills” of Autism Spectrum Quotient. These results indicate that functional connectivity analysis using MEG is useful to assess the default mode network associated with atypical cognitive property specific to autism.
