Abstract
Denture plaque is an important factor in the pathogenesis of denture stomatitis. Candida species can be found in high frequencies in denture plaque related to denture stomatitis. This study was carried out to investigate the antifungal activity and the effects on mechanical properties of dental materials of mouthwashes containing berberine hydrochloride, which has antifungal activity against C. albicans, C. tropicalis, and C. glabrata.
The results indicated that the mouthwashes containing berberine hydrochloride had antifungal activity (fungicidal activity and fungistatic activity with short-term exposure) and a slight effect on the color stability of acrylic resin plates, high wear resistance plastic teeth, and surface roughness of acrylic resin plates.
