直記式 Flow-Volume Curve Recorder によるMEFV曲線の各指標の正常予測式とその正常範囲について

抄録

This study was carried out for the purpose of establishing “normal” prediction equations and “normal” limits of the parameters of MEFV (maximal expiratory flow-volume) curve. The subjects were 114 females and 227 males, ranging in age from 19 to 68 years, and were selected from 2396 employees of the Ministry of Posts and Telecommunications on the basis of the following criteria:
1) no respiratory symptoms
2) no history of cardiorespiratory diseases
3) no history of smoking
4) normal chest X-ray findings
5) %FVC>80%, FEV 1.0%>70%,
6) adequate maximal expiratory effort at the test
MEFV curves were recorded using a direct writing flow-volume curve recorder. Forced expiratory vital capacity, one second forced expiratory volume, maximal flow at 50 per cent (T) and 25 per cent (V₂₅) of the forced vital capacity, and the ratio of V₅₀ to V₂₅ were measured. The correlation coefficients of V₅₀, V₂₅ and V₅₀/ V₂₅ were calculated with age, height, weight and obesity rate. All of three parameters correlated with age and height significantly. Especially, we emphasized that V₂₅ and V₅₀/V₂₅ correlated with obesity significantly. “Normal” prediction equations of V₅₀, V₂₅ and V₅₀/V₂₅ were decided by the least squares method (Table 4). The “normal” limits of predicted values were also presented (Table 5).