日本胸部疾患学会雑誌
Online ISSN : 1883-471X
Print ISSN : 0301-1542
ISSN-L : 0301-1542
肺真菌症発症要因に関する臨床的検討
松島 敏春沖本 二郎矢木 晋繁治 健一加藤 収溝口 大輔小林 武彦田野 吉彦副島 林造中嶋 健博藤井 芳郎原 義人
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1979 年 17 巻 12 号 p. 798-805

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Factors causing pulmonary mycotic infection in 31 patients over the last five years were studied. In terms of host factors, the mechanisms of fungal infection to the lung mere classified in three groups as primary, secondary, and saprophytic infection. Primary pulmonary mycosis was a fungal infection to the lung in asymptomatic patients with no obvious underlying diseases. Three patients with nodular lesions on chest X-ray detected by annual survey belonged to this group.
Secondary pulmonary mycosis was an opportunistic fungal infection in patients in deteriorated condition with severe underlying diseases and those treated with steroid hormones, antineoplastic drugs, and antimicrobials. Fungal infections in 13 patients belonging to this group were detected by microscopic examination of the autopsy specimen, which revealed candida sp., aspergillus sp., mucor sp., cryptococcus sp., or torulopsis graburata.
The important host factors in saprophytic mycosis were the existence of abnormal spaces in the lung, such as cavities, bullae, cysts, and bronchiectasis. Most of the 15 patients belonging to this group had fungus ball formation by aspergillus sp. in open negative cavities in pulmonary tuberculosis.
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