肺胞石灰沈着を伴う Bleomycin 肺臓炎の1剖検例

抄録

A 43-year-old male patient with esophageal cancer was given preoperative treatment with irradiation and bleomycin. Soon after the esophageal resection, the patient showed hypercalcemia and developed progressive fatal respiratory failure.
Autopsy revealed bleomycin-induced pneumonitis with severe exudation and hyaline membranous deposition of calcium in the alveoli. Calcium deposits were also found in the kidney and gastric membrane. Therefore, it was suggested that the mechanism of alveolar calcification in the present case was due to dystrophic as well as metastatic calcification.