電気的インピーダンス法による肺の局所換気動態の検討特にフロー・ボリューム曲線について

抄録

A six-channel scanning impedance pneumograph (Nihon Kohden Kogyo Co., Ltd., OGR-5100S) was applied to the assessments of changes in regional flow ans volume in various lung fields. A co-axial electrode (NI-601V), which consists of a thin polyester disc and electroconductive gel, made it possible to obtain stable recordings of regional respiratory ΔZs on body exertion. Changes in regional respiratory ΔZs and the derivatives of the ΔZs during forced expiration from TLC to RV were recorded simultaneously on X-Y co-ordinates, which were considered to represent regional flow-volume relationships. Also, they were each recorded on a polygraph simultaneously with overall flow and volume for quantitative analysis of the time sequences. Measurements were performed on 8 healthy laboratory workers and patients with various pulmonary disorders.
In healthy subjects it was observed that neither regional flow nor volume showed a significant difference between right and left lung fields, whereas those obtained in the upper lung fields differed significantly from those recorded in the lower zone. Regional differences in ventilatory functions in the diseased lungs, which were hardly recognized in overall flow-volume curves, were well reflected by the regional flow-volume curves.
It was demonstrated that the present impedance method could be successfully used for evaluating regional ventilatory function in both normal and diseased lungs.