肺における表面張力

II. 無気肺の表面活性

抄録

We have studied the change in surface activity in pathological conditions. At first, in this study the change in surface activity was investigated by Pattle's method in atelectasis induced in rabbits by prombage of pieces of sponge or by artificial pneumothorax. The decrease in SR was brought about 24 hous after the atelectasis and it returned to the normal value by several inflations of atelectatic lung prior to resection. This recovery of surface activity was observed even in the lung which was atelectatic for 8 days. However, the surface activity remained low when the atelectatic lung was inflated several times after washing out the blood in pulmonary vessels with saline. These results indicate that pulmonary circulation appears to be necessary in recovery of the lowered surface activity observed in chronic simple atelectasis.