Abstract
An 83-year-old woman visited our hospital because of a breast abnormality revealed at a breast cancer screening examination. On palpation, a 3.0-cm, elastic, hard tumor was observed in the left breast. Mammography revealed a round, indistinct tumor shadow in the inner lower region of the left breast. Ultrasonography showed a 35×28-mm low echoic lesion at the 7-8 o'clock position in the left breast. Core needle biopsy showed invasive ductal carcinoma. Therefore, we performed mastectomy with axillary dissection. Histologically, massive necrosis was observed in the tumor mass. Because only a few viable carcinoma cells remained around the area of necrosis, the tumor could be diagnosed as a solid tubular carcinoma with massive infarction by referring to the results of a preoperative biopsy specimen. The nuclear grade was 2, and lymph node micrometastasis was confirmed. She tested positive for estrogen and progesterone receptors, and the human epidermal growth factor receptor-2 score was 0. Although she had had multiple lung metastases 1 year and 9 months after the surgery, the lesion disappeared following administration of endocrine therapy, which has been administered until currently.
Herein, we report this very rare case of breast cancer associated with infarcted necrosis.
