Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
Case Reports
A Case of Multiple Bone Metastases after Surgery for Gastric Cancer for which Chemotherapy and Irradiation were Significantly Effective
Ayana GOTOTakahito ADACHIYoshiyuki SASAKIMakoto YAMADA
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2019 Volume 80 Issue 1 Pages 74-78

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Abstract
A 59-year-old man who was aware of appetite loss and tarry stool was referred to our hospital for close exploration and treatment. Esophagogastroduodenoscopy revealed an easily bleeding type 3 tumor with infiltration into the esophagus on the lessor curvature side of the cardiac part of the stomach. A contras-enhanced abdominal CT scan showed bulky lymph node swelling as well. We conducted two courses of S-1 (80mg/m2) + DTX (60mg/m2) regimen, followed by total gastrectomy (D2) and splenectomy. The therapeutic effect was rated Grade 0, but adjuvant chemotherapy was not given. When and year and 5 months had elapsed after the operation, he was aware of left shoulder joint pain following he tumbled down. Bone scintigraphy revealed multiple bone metastases. Then adjuvant chemotherapy with S-1 (80mg/m2) + DTX (60mg/m2) and radiation therapy were started. For 7 years after completion of a total of 11 courses of the chemoradiotherapy, we followed the patient by only observation of his clinical course and confirmed his bone metastases to have completely disappeared. We discontinued to follow him 11 years after the operation.
The frequency of bone metastasis from gastric cancer is low and the prognosis is generally poor. We present a patient with gastric cancer who developed bone metastases one year and 5 months after the operation and was completely cured from the disease.
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© 2019 Japan Surgical Association
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