Abstract
The clinical, pathological and cytological features of a patient with undifferentiated carcinosarcoma of the uterus are reported. The patient had a past history of squamous carcinoma of the uterine cervix 4 years previously, for which irradiation therapy had been carried out.
Three kinds of atypical cells detected in the smear consisted of the following distinguishing features;
1) Atypical fibrous cells with hyperchromatic nucleiand marked anisocytosis.
2) Flat bizzare cells with broad cytoplasma, associated with anisonucleosis and mutual inclusion.
3) Fpithelial sheet of atypical small cells with prominent nucleolus and chromatin aggregation, occasionally with mucous vacuoles in the cytoplasm.
These different cytological features were compared respectively with the corresponding elements of the histopathological specimens which had been proved to be a tumor that had arisen independenly in the endo metrium, being different from the previous squamous cancer of the cervix.And the former one cell group, shown above, was found to have been delivered from the sarcomatous element, and the latter two cell groups were found to be of carcinoma origin.
In addition, it is briefly discussed whether the irradiation given4years previously may have played a role in carcinogenesis of the present carcinosarcoma of the uterus or not.
