Cytohormonal evaluation was made on vaginal smears and smears of urinary sediment taken from 56 premenopausal and 16 postmenopausal castrated women.
1) The atrophic type appeared soon after castration in the normally menstruating women. The breakdown after 25 weeks was 37.0% atrophic type, 55.6% intermediate type and 7.4% estrogenic type.
2) There were a few cases which later turned out to be of the estrogenic type, although they had initially been of the intermediate type.
3) Histological findings of vaginal epithelium 16 weeks after castration gave such a breakdown which was 11.8% estrogenic type, 50.0% intermediate type, and 38.2% atrophic type.
4) The foregoing results suggested the existence of some mechanism which assists the vaginal epithelium in proliferating and maturating after castration.
5) Also suggested was the existence of a slightestrogen secretory function in the menopausal ovary.
6) Serum estradiol was as low as 30-60 pg/ml one week after castration.
7) Changes in the smears of urinary sediment kept pace with those of the vaginal smears, and they were found satisfactory as test objects for cytohormonalevaluation.
