1989 Volume 28 Issue 3 Pages 409-414
A rare case of ovarian adenosarcoma was studied with special reference of cytology and histopathology. The tumor developed in the left ovary of a 46-year-old house wife, was first considered to be inoperable. The biopsy specimen revealed an endometriosis like lesion, but with some atypicalities in stromal cells. One year later, the tumor was removed together with the uterus, adnexa, and omentum. Macroscopically, the tumor was polypoid and multiple, weighing 500 g altogether. One cut section, these growths were brownish and mostly solid, but with cystic area in parts. The tumor was consisted histologically of benign-appearing endometriosis glands lying in a cellular and atypical stroma. No tumor cells were found in a scanty ascites, but atypical mesenchymal cells were seen in the imprint smears corresponding to the histological features. Although no mitosis was found, the tumor was diagnosed as adenosarcoma, because the stroma tended to form cellular collars around the glandular structures. The diagnosis was ascertained by examing the recurrent tumor which appeared about three years later. The recurrent tumor was similar macroscopically and microscopically to the original tumor, but with some mitoses (11/10 HPF) in the stromal cells.
