1989 Volume 28 Issue 3 Pages 415-419
Gartner's duct cysts arise from the vestigial remains of the Wolffian canals; the so-called Gartner's ducts. They are generally located on the anterolateral aspect of the vagina. A case of mesonephric adenocarcinoma (clear cell adenocarcinoma) arising from a Gartner's duct cyst was reported. A 46-year-old woman was admitted with complaints of micturition pain and frequent urination, and a cystic tumor located in the anterior wall of the vagina, was detected. Aspiration cytology of fluid from the mass lead to the diagnosis of a class V adenocarcinoma, and cystectomy was subsequently performed. The cystic tumor was located between the urethra and the vagina, and the urethra was surrounded by the tumor circumferentially. The aspiration cytology revealed clear cells, dark cells, and hobnail cells, which are haracteristic features of clear-cell adenocarcinoma. Mirror ball patterns were also identified. The diagnosis based on the histological findings was clear-cell denocarcinoma, and a PAS-alcian blue stain revealed droplets of glycogen in the cytoplasm. The epithelium of the cystic wall consisted of the single-layered or multilayered cuboidal cells of Gartner's duct, and followed the adenocarcinoma continuously. The mucosa of the urethra and the vagina was intact.