The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
A case of Burkitt's lymphoma with t (2; 8), diagnosed by lymph node aspiration cytology
Junko KAYAOJun-ichi TAMARUShosuke SUNAMITakeyuki SATOTadashi SAITOYasuhiko FUKUMOTOAtsuo MIKATANoboru TANAKA
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1998 Volume 37 Issue 5 Pages 520-524

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Abstract
Background: Burkitt's lymphoma has been classified into two subtypes: African and Non-African type, according to genetic differences, and chromosomal abnormalities. The present case is a rare Non-African type, characterized by dislocation of chromosome t (2; 8).
Case: A 6-year-old boy, had been diagnosed as Burkitt's lymphoma by lymph node aspiration cytology in 1987. Histopathological findings showed a significant starry-sky appearance. Immunohistochemical findings and flow cytometrical and karyotype analysis data were described. Neoplastic cells were decided to be B-cell type by various examination. They had a basophilic cytoplasm with microvesicular structure, characterized by positive staining for lipid. Karyotype analysis disclosed a t (2; 8) dislocation. Immunological examination showed no elevation of Epstein-Barr virus (EBV) antibody.
Conclusion: These features appeared to be compatible with those seen in Extra-African type Burkitt's lymphoma. The patient is now uneventful and under follow-up.
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© The Japanese Society of Clinical Cytology
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