2023 年 39 巻 3 号 p. 74-80
Squamoid eccrine ductal carcinoma (SEDC) is a subtype of squamous cell carcinoma. It is a malignant tumor composed of squamous cell carcinoma and adenocarcinoma. The first three reported cases of SEDC were described in 1997 by Wong et al. Superficial diagnostic biopsies often lead to the misdiagnosis of SEDC as cutaneous cell carcinoma. Herein, we report a rare case of SEDC with repeated local recurrence following resection that was resolved with drug therapy. In our patient, SEDC was unresectable after the fifth recurrence; however, the tumor disappeared after combination treatment with chemotherapy and an immune checkpoint inhibitor. Herein, we present the case along with relevant literature.