2020 年 20 巻 3 号 p. 159-164
In dentistry, mechanical analysis applied to dentition is an important issue regardless of whether the evaluation concerns a natural or artificial tooth. This paper describes the mechanobiology of periodontal tissues that receive and respond to occlusal forces and orthodontic treatment forces to maintain a healthy homeostasis. This paper also discusses the effects of accelerating orthodontic teeth movement by the resonance vibration stimulation.
The specific biological response to a mechanical stress is determined by both the properties and magnitude of the applied mechanical stress, in addition to the duration and interval of application to the target cells at the targeted site. Therefore, it is essential to elucidate cell-specific and stimulus-specific biomechanics at the cellular and molecular levels.
This work adds to an emerging field termed mechanobiology that focuses upon understanding mechanosensor /mechanoreceptor molecules that receive signals from mechanical stress, and the mechanism－known as mechanotransduction－by which mechanical stress signals are transmitted into cells. Research outcomes from this field are expected to yield critical information for keeping teeth, bones, and muscles healthy, and increasing the quality of life.
