Abstract
This paper presents a simulation technique of yeast cultivation and ethanol fermentation on a commercially available process
simulator. In general, the simulation of microorganism cultivation on the process simulator is not possible because a material
data of the microorganism is not registered in the simulator. If all of the data required is collected and installed to the
simulator, the simulation of the microorganism cultivation will be achieved on it. Yeast which is a widely known in industrial
field was chosen as a model microorganism. The data of yeast was collected by analytical measurement and literature survey,
followed by a composition of model yeast and reaction formulas were determined. All data associated the yeast was
completely installed in to the simulator. Process of the yeast cultivation and ethanol fermentation was demonstrated on the
simulator as a case study. The success of the simulation of the case study was confirmed. Estimation of input substrate
quantity and prediction of generated heat amount of microbial reaction become possible on the proposed method. This
method can provide diversification and advancement of simulation technique for process evaluation associated microbial
reaction.
