Abstract
The post operative infection fregnency have been reported in 10-20% of digestive tract surgery, because of contamination from gut. The progress in antibiotic therapy hoped to diminish the incidence of postoperative infection, but in the otherhand, extended operative indication to aged people, compromised host and increased lymphonode dessection made no significant difference in incidence of postoperative infection. Moreover, MRSA made a new aspect of surgical infection and nosocomial infection from late half of 1980's in choice of antibiotics.