Abstract
Microscopic polyangiitis （MPA） is a systemic vasculitis that is positive for anti-neutrophil cystoplasmic antibody （ANCA）. We report two cases of multiple oral ulcers associated with MPA. In case 1, after being diagnosed with MPA based on Myeloperoxidase （MPO）-ANCA positive and sural nerve biopsy findings, multiple ulcers appeared in the oral cavity. In case 2, the patient showed systemic edema, and multiple ulcers were found in the oral mucosa during close examination at the internal medicine. The patient was diagnosed as MPA because MPO-ANCA was positive. The ulcer disappeared after chemotherapy. This disease should also be considered when multiple ulcers in the oral cavity are observed.
