Abstract
Amyloidosis is a disease of unknown cause, in which amyloid proteins are deposited in various body organs and tissues, causing dysfunction. This time, we experienced a case of amyloidosis in the labial mucosa associated with multiple myeloma. The case involved a 50-year-old man who had nodules in his upper and lower lips at his initial visit and tissue biopsy confirmed amyloid deposits. Despite it having been 9 years since he made his first visit, the lesions on his lips have not changed. In Japan, there have been many cases of oral amyloidosis occurs in the tongue, while it rarely occurs in the lips.
