先天性胆道閉塞症術後の肝組織の推移 : 根治手術時と外瘻閉鎖術時との比較

抄録

In 26 corrected cases with biliary atresia, we examined and compared a histology of the liver specmen taken at the time of radical operation and closure of the jejunal stoma. The following findings were seen in the second biopsy specimen: 1. In most of the cases, fibrosis of the liver progressed. 2. Proliferated bile ducts in the portal area reduced in number. It is of interest that on bile ducts can be seen in portal area in 8 cases. 3. Persistent round cell infiltration was noted in about a half of cases. 4. Bile stasis, characteristic giant cells and foci of extramedullar hematopoiesis in the liver were completely disappeared, 5. Liver cell cords and limiting plates showed marked improvement from previous disarrangement.