日本小児外科学会雑誌
Online ISSN : 2187-4247
Print ISSN : 0288-609X
ISSN-L : 0288-609X
鎖肛に関する基礎的研究 : I.実験モデルとしての鎖肛ブタの検討
古川 敏紀菅沼 靖澤口 重徳北村 享俊大川 治夫坂庭 操
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1982 年 18 巻 4 号 p. 793-801

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For the purpose of investigating the possibility to establish an experimental animal model, the anorectal malformations of swine was studiea The questionaires were sent to 404 swineries in order to know the actual occurrence of imperforate anus in swines. The statistical analysis on their reports revealed that an imperforate anus was indemnified per 566.6 swine deliveries (the incidence was 0.81%), and that those anomalies had predominant tendency in hereditary occurrence. Close similarities were also demonstrated between swine and human being in the types of anorectal malformations. In conclusion, those swine with imperforate anus can be used as an appropriate experimental animal model and they are considered to be very useful material for studying the pathogenesis and for devising the treatment method of human anorectal malformations.

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© 1982 特定非営利活動法人 日本小児外科学会
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