A case of Meckel's diverticulitis with abscess formation diagnosed by ultarsound is reported. This is the first case report diagnosed by ultrasound so far. A 5-year-old girl presented to our hospital with 3 days history of high fever and right hypochondralgia. In newborn period, she had undergone abdominal drainage with the same symptoms with an intraabdominal abscess of unknown origin. On admission, ultrasonographic study revealed a cystic lesion at the right hypochondral region. A Meckel's diverticulum was diagnosed with ultrasonically guided percutaneous contrast medium injection to the abscess lumen. Drainage catheter was inserted to the diverticulum using a real time puncture transducer. Subsequently the diverticulum was resected radically. Meckel's diverticulum in the neonate is rare. This case showed unusual complication of diverticulitis in the newborn period. The diagnosis of Meckel's diverticulum prior to laparotomy is difficult and uncertain though several diagnostic techniques have been employed including barium examination of the small intestine, angiography and isotope scanning. However in this report the diverticulum was possibly diagnosed preoperatively by ultrasound. The usefulness of this method in diagnosis of this disease has been demonstrated.