胆道閉鎖症吻合不能型症例における肝内胆管病変(第1報 B/F比と予後)

抄録

The intrahepatic bile duct of so-called uncorrectable type of biliary atresia was studied histopathologically using image processing system. Total area of all intrahepatic bile ductuli (B), which contains both lumen and epithelium, in one field and the total area of all fibrotic area (F), which contains bile ductuli and vesseles, in one field were measured in wedge biopsy specimens obtained from 25 patients. B/F ratio was calculated and used as an indicator which means the percentage of the area of intrahepatic bile ducts in the interstitial fibrotic area of Glisson's sheath. B/F ratio was low in the patients was showed excretion of a large amount of bile after the operation, while the ratio was high in those who showed excretion of small amount of bile after the operation. The present study suggested that there was a close correlation between B/F ratio of liver biopsy specimen and the postoperative bile flow.