Recent Results from the National Wilms' Tumor Study(第21回日本小児外科学会, 招待講演I)

抄録

Preliminary results from NWTS-3 currently suggest that (1) a 10 weeks course of AMD and VCR for "favorable histology" Stage I Wilms' tumor is as effective as a 6 months course, (2) flank irradiation is not statistically advantageous for "favorable histology" Stage II tumors, (3) ADR does not significantly improve outcome for "favorable histology" Stage II or III tumors, (4) Stage I anaplastic Wilms' tumors probably do not require radiotherapy or intensified chemotherapy, and (5) the prognosis for Stage I CCSK is markedly improved by radiotherapy and intensified chemotherapy. A new classification of nephroblastomatosis is briefly introduced, that has both practical and theoretical importance with relation to Wilms' tumor and other childhood renal tumors.