This study was designed & purposed to examine whether the mechanism of bile secretion is normal or not after hepatic portoenterostomy for biliary atresia. Seven patients who have undergone a Suruga II portoenterostomy were studied. In five of six patients, bile volume (Y) showed a correlation with bile salt excretion (X) (Y=0.03-0.167x+0.01-0.08, R=0.648-0.892), and Y intercrept were always positive (0.01-0.08 ml/min.). This evidence suggested a presence of both bile salt dependant and independant bile secretion machanism. Bilirubin excretion showed no correlation with bile salt excretion (R=0.357), but cholesterol exretion (Y) showed a correlative relationship with bile salt excretion (X). (Y=0.014x+0.07, n=49, R=0.801) Phospholipid (Y) had a correlation with bile salt excretion (X). (Y=0.092x+0.012, n=48, R=0.952) The results suggest that the mechanism of bile secretion is almost normal after hepatic portoenterostomy for biliary atresia.
