Malignant ovarian tumors of childhood are infrequent and most of them are of germ cell origin. The literature on malignant pediatric ovarian tumors makes it difficult for the physiciam confronting this disease to find and utilize an optimal therapeutic approach. In our hospital, malignant mixed germ cell tumor, combined with dysgerminoma and endodermal sinus tumor, in a 8-year-old female was treated without sign of recurrence, by surgery, radiation (2,970 rad at lower abdomen, and 3,000 rad at para-aortic region), and VAB therapy (Vinblastine, Actinomycin-D, and Bleomycin). With a review of literature, embryology, classification, treatment, and prognosis of the mixed germ cell tumor were briefly discussed.
