An 8-month-old girl with stage II neuroblastoma detected by neuroblastoma mass screening who developed bone and bone marrow metastases 12 months after the teatment is presented. This patient had regional lymph nodes involvment when she was operated. It is generally accepted that the presence of involved lymph nodes worsens the prognosis in stage II neuroblastoma. Therefore, stage II neuroblastoma with regional lymph nodes involvement should be treated with caution.
